2024

1. Tunable cell differentiation via reprogrammed mating-type switching
   Heng YC, Kitano S, Susanto AV, Foo JL and Chang MW
   Nature Communications 15(1): 8163 (2024)
2. Prodrug-conjugated tumor-seeking commensals for targeted cancer therapy
   Shen H, Zhang C, Li S, Liang Y, Lee LT, Aggarwal N, Wun KS, Liu J, Nadarajan SP, Weng C, Ling H, Tay JK, Wang DY, Yao SQ, Hwang IY, Lee YS and Chang MW
   Nature Communications 15(1): 4343 (2024)
3. Microbial engineering strategies to utilize waste feedstock for sustainable bioproduction
   Aggarwal N, Pham HL, Ranjan B, Saini M, Liang Y, Hossain GS, Ling H, Foo JL and Chang MW
   Nature Reviews Bioengineering 2(2): 155 (2024)
4. Engineered microbial consortia for next-generation feedstocks
   Hossain GS, Liang Y, Foo JL and Chang MW
   Biotechnology Notes 5:23 (2024)
5. MFSD7c functions as a transporter of choline at the blood–brain barrier
   Nguyen XTA, Le TNU, Nguyen TQ, Thi Thuy Ha H, Artati A, Leong NCP, Nguyen DT, Lim PY, Susanto AV, Huang Q, Fam L, Leong LN, Bonne I, Lee A, Granadillo JL, Gooch C, Yu D, Huang H, Soong TW, Chang MW, Wenk MR, Adamski J, Cazenave-Gassiot A and Nguyen LN
   Cell Research 34(3): 245 (2024)
6. Organ-on-chip technology: Opportunities and challenges
   Srivastava SK, Foo GW, Aggarwal N and Chang MW
   Biotechnology Notes 5:8(2024)

2023

1. An Engineered Probiotic Produces a Type III Interferon IFNL1 and Reduces Inflammations in in vitro Inflammatory Bowel Disease Models
   Chua KJ, Ling H, Hwang IY, Lee HL, March JC, Lee YS and Chang MW
   ACS Biomaterials Science and Engineering 9(9): 5123 (2023)
2. A spotlight on global collaboration in the Sc2.0 yeast consortium
   Dai J, Yang H, Pretorius IS, Cai P, Shen CY, Chang MW and Yuan Y
   Cell Genomics 3(11): 100441 (2023)
3. Establishing chromosomal design-build-test-learn through a synthetic chromosome and its combinatorial reconfiguration
   Foo JL, Kitano S, Susanto AV, Jin Z, Lin Y, Luo Z, Huang L, Liang Z, Mitchell LA, Yang K, Wong A, Cai Y, Cai J, Stracquadanio G, Bader JS, Boeke JD, Dai J and Chang MW
   Cell Genomics 3(11): 100435 (2023)
4. Synthetic biology: learning the way towards high-precision biological design
   Kitano S, Lin C, Foo JL, Chang MW
   PLOS Biology 21(4): e3002116 (2023)
5. Engineering Escherichia coli for diagnosis and management of hyperuricemia
   Gencer G, Mancuso C, Chua KJ, Ling H, Costello CM, Chang MW, March JC
   Frontiers in Bioengineering and Biotechnology 11: 1191162 (2023)
6. Engineering of a probiotic yeast for the production and secretion of medium-chain fatty acids antagonistic to an opportunistic pathogen Candida albicans
   Ling H, Liu R, Sam QH, Shen H, Chai LYA, Chang MW
   Frontiers in Bioengineering and Biotechnology 11: 1090501
7.  FELICX: A robust nucleic acid detection method using flap endonuclease and CRISPR-Cas12
   Aggarwal N, Liang Y, Foo JL, Ling H, Hwang IY, Chang MW
   Biosensors and Bioelectronics 222: 115002 (2023)
8.  Microbiome and human health: current understanding, engineering, and enabling technologies
   Aggarwal N, Kitano S, Puah GRY, Kittelmann S, Hwang IY, Chang MW
   Chemical Reviews 123 (1): 31-72 (2023)
9.  Synthetic biology meets machine learning
   Sieow BFL, De Sotto R, Seet ZRD, Hwang IY, Chang MW
   Methods in Molecular Biology 2553: 21-39 (2023)
10. Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism
    Koh E, Hwang IY, Lee HL, De Sotto R, Lee JWJ, Lee YS, March JC, Chang MW
    Nature Communications 13: 3834 (2022)

2022

1. Mitochondrial engineering of Yarrowia lipolytica for sustainable production of α-bisabolene from waste cooking oil
   Zhu K, Zhao B, Zhang Y, Kong J, Rong L, Liu S, Wang Y, Zhang C-Y, Xiao D, Foo JL, Yu A
   ACS Sustainable Chemistry and Engineering 10(29): 9644-9653 (2022)
2. Synthetic biology for the sustainable production of biochemicals in engineered microbes
   Shi S, Wang J, Ling H
   Frontiers in Bioengineering and Biotechnology 10: 984875 (2022)
3. Principles in microbiome engineering
   Chang MW
   Wiley-VCH GmbH (2022)
4. Dominant negative TRAF3 variant with recurrent Mycobacterium abscessus infection and bronchiectasis
   Liew MF, Lim HF, Liang MC, Lim I, Tan Z, Tan RYM, Sam QH, Soe WM, Tay SH, Xu S, Chang MW, Foo R, Soong TW, Ravikumar S, Chai LYA
   Open Forum Infectious Diseases 9(8): ofac379 (2022)
5. Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism
   Koh E, Hwang IY, Lee HL, De Sotto R, Lee JWJ, Lee YS, March JC, Chang MW
   Nature Communications 13: 3834 (2022)
6. Engineered microbial systems for advanced drug delivery
   Shen HS, Aggarwal N, Wun KS, Lee YS, Hwang IY, Chang MW
   Advanced Drug Delivery Reviews: 114364 (2022)
7. Potential use of microbial engineering in single-cell protein production
   Balagurunathan B, Ling H, Choi WJ, Chang MW
   Current Opinion in Biotechnology 76: 102740 (2022)
8. Design and fabrication of field-deployable microbial biosensing device
   Pham HL, Ling H, Chang MW
   Current Opinion in Biotechnology 76: 102731 (2022)
9. Living building blocks
   Wun KS, Hwang IY, Chang MW
   Nature Materials 21 (4): 382-383
10. Transporter-driven engineering of a genetic biosensor for the detection and production of short-branched chain fatty acids in Saccharomyces cerevisiae
    Miyake R, Ling H, Foo JL, Fugono N, Chang MW
    Frontiers in Bioengineering and Biotechnology (2022) In press

2021

1. Synthetic biology: at the crossroads of genetic engineering and human therapeutics-a Keystone Symposia report
   Cable J, Leonard JN, Lu TK, Xie Z, Chang MW, Fernandez LA, Lora JM, Kaufman HL, Quintana FJ, Geiger R, Lesser CF, Lunch JP, Hava DL, Cornish VW, Lee GK, DiAndreth B, Fero M, Srivastava R, Coster TD, Roybal KT, Rackham OJL, Kiani S, Zhu I, Hernandez-Lopez RA, Guo T, Chen WCW
   Annals of the New York Academy of Sciences. 1506(1): 98-117 (2021)
2. A newly established virus induced gene silencing via seed imbibition for functional genomics at the early germination stages in cotton
   Shi G, Hao M, Tian B, Cao G, Chen W, Zhang Q, Zhang Y, Ling H, Li J, Xie Z, Wei F
   Industrial Crops and Products. 172:114040 (2021)
3. Driving innovation in biotechnology with private-public partnerships: a Singapore perspective
   Lee HL, Vasitvas K
   Biotechnology Notes 2: 59-62 (2021)
4. Metabolic engineering of microbes for monoterpenoid production
   Zhu K, Kong J, Zhao B, Rong L, Liu S, Lu Z, Zhang C, Xiao D, Pushpanathan K, Foo JL, Wong A, Yu A.
   Biotechnology Advances 53: 107837 (2021)
5. Hybrid promoter engineering strategies in Yarrowia lipolytica: isoamyl alcohol production as a test study
   Zhao Y, Liu S, Lu L, Zhao B, Wang S, Zhang C, Xiao D, Foo JL, Yu A
   Biotechnology for Biofuels 14: 149 (2021)
6. Simultaneous improvement of limonene production and tolerance in Yarrowia lipolytica through tolerance engineering and evolutionary engineering
   Li J, Zhu K, Miao M, Rong L, Zhao Y, Li S, Ma L, Li J, Zhang C, Xiao D, Foo JL, Yu A
   ACS Synthetic Biology 10(4): 884-896 (2021)
7. Next-generation metabolic engineering of non-conventional microbial cell factories for carboxylic acid platform chemicals
   Li J, Rong L, Zhao Y, Li S, Zhang C, Xiao D, Foo JL, Yu A
   Biotechnology Advances 43: 107605 (2020)
8. Ectopic overexpression of a cotton plastidial Na+ transporter GhBASS5 impairs salt tolerance in Arabidopsis via increasing Na+ loading and accumulation
   Myo T, Tian B, Zhang Q, Niu S, Liu Z, Shi Y, Cao G, Ling H, Wei F, Shi G
   Planta 252(3): 41 (2020)
9. Heterologous expression of cyanobacterial gas vesicle proteins in Saccharomyces cerevisiae
   Jung H, Ling H, Tan YQ, Chua NH, Yew WS, Chang MW
   Biotechnology Journal. 9: e2100059 (2021)
10. Engineered probiotics modulate the endocannabinoid system
    Hwang IY, Kim HR, De Sotto R, Chang MW
    Biotechnology Notes 2: 33-38 (2021)
11. The divergent immunomodulatory effects of short chain fatty acids and medium chain fatty acids
    Sam QH, Ling H, Yew WS, Tan Z, Ravikumar S, Chang MW, Chai LYA
    International Journal of Molecular Sciences 22(12): 6453 (2021)
12. Future trends in synthetic biology in Asia
    Mao N, Aggarwal N, Poh CL, Cho BK, Kondo A, Liu C, Yew WS, Chang MW
    Advanced Genetics 2: e1003 (2021)
13. Development of a polymer-based antimicrobial coating for efficacious urinary catheter protection
    Low JL, Kao P H-N, Tambyah PA, Koh GLE, Ling H, Kline KA, Cheow WS, Leong SSL
    Biotechnology Notes 2: 1-10 (2021)
14. Biosynthesis of commodity chemicals from oil palm empty fruit bunch lignin
    Lo T-M, Hwang IY, Cho H-S, Fedora RE, Chng SH, Choi WJ, and Chang MW
    Frontiers in Microbiology 12: 663642 (2021)

2020

1. Tweak to Treat: Reprograming Bacteria for Cancer Treatment
   Sieow BFL, Wun KS, Yong WP, Hwang IY, Chang MW
   Trends in Cancer, 7(5): 447-464 (2020).
2. Genetic biosensor design for natural product biosynthesis in microorganisms
   Hossain GS, Saini M, Miyake R, Ling H, Chang MW
   Trends in Biotechnology. 38 (7): 797-810 (2020)
3. Engineering probiotics for therapeutic applications: recent examples and translational outlook
   Aggarwal N, Breedon A, Davis C, Hwang IY, Chang MW
   Current Opinion in Biotechnology. 65: 171-179 (2020)
4. Mechanism-Driven Metabolic Engineering for Bio-Based Production of Free R-Lipoic Acid in Saccharomyces cerevisiae Mitochondria
   Chen B, Foo JL, Ling H, Chang MW
   Frontiers in Bioengineering and Biotechnology. 8: 965 (2020). doi.org/10.3389/fbioe.2020.00965
5. Engineering an Alcohol-Forming Fatty Acyl-CoA Reductase for Aldehyde and Hydrocarbon Biosynthesis in Saccharomyces cerevisiae
   Foo J L, Rasouliha B H, Susanto A V, Leong S S J and Chan M W
   Frontiers in Bioengineering and Biotechnology. 8: 585935 (2020). doi.org/10.3389/fbioe.2020.585935
6. Development of a proline-based selection system for reliable genetic engineering in Chinese Hamster Ovary Cells
   Sun T, Kwok WC, Chua KJ, Lo T-M, Potter J, Yew WS, Chesnut JD, Hwang IY, and Chang MW
   ACS Synthetic Biology. (2020) (In press)
7. Toolkit development for cyanogenic and gold biorecovery chassis Chromobacterium violaceum
   Liow LT, Go MK, Chang MW, Yew WS
   ACS Synthetic Biology. 2020, 9, 4, 953-961 (2020)
8. Engineering Yarrowia lipolytica towards food waste bioremediation: Production of fatty acid ethyl esters from vegetable cooking oil
   Ng TK, Yu AQ, Ling H, Juwono NK, Choi WJ, Leong SS, Chang MW
   Journal of Bioscience and Bioengineering. 129(1): 31-40 (2020)

2019

1. Engineering commensal bacteria to rewire host-microbiome interactions
   Hwang IY, Chang MW
   Current Opinion in Biotechnology 62:116-122 (2019)
2. Phage-boosted chemotherapy
   Aggarwal N, Hwang IY, Chang MW
   Nature biomedical engineering 3(9):680-681 (2019)
3. A novel synchronization approach using synthetic magnetic Escherichia coli
   Ling H, Chang MW
   Synthetic and Systems Biotechnology. 4(3):130-1 (2019)
4. Meta-omics-and metabolic modelling-assisted deciphering of human microbiota metabolism
   Sieow BF, Nurminen TJ, Ling H, Chang MW
   Biotechnology journal. 30:1800445 (2019)
5. Building a global alliance of biofoundries
   Hillson N, Caddick M, Cai Y, Carrasco JA, Chang MW, Curach NC, Bell DJ, Le Feuvre R, Friedman DC, Fu X, Gold ND, Herrgård MJ, Holowko MB, Johnson JR, Johnson RA, Keasling JD, Kitney RI, Kondo A, Liu C, Martin VJJ, Menolascina F, Ogino C, Patron NJ, Pavan M, Poh CL, Pretorius IS, Rosser SJ, Scrutton NS, Storch M, Tekotte H, Travnik E, Vickers CE, Yew WS, Yuan Y, Zhao H, Freemont PS
   Nat Communications. 10(1):2040 (2019)
6. Synthetic genetic circuits for programmable biological functionalities
   Xia PF, Ling H, Foo JL, Chang MW
   Biotechnol Advances pii: S0734-9750(19)30074-6 (2019)
7. Synthetic Biology Toolkits for Metabolic Engineering of Cyanobacteria
   Xia PF, Ling H, Foo JL, Chang MW
   Biotechnol Journal. e1800496. (2019)

2018

1. An oleaginous yeast platform for renewable 1-butanol synthesis based on a heterologous CoA-dependent pathway and an endogenous pathway
   Yu A, Zhao Y, Pang Y, Hu Z, Zhang C, Xiao D, Chang MW, Leong SSJ
   Microb Cell Fact 17(1):166 (2018)
2. Synthetic Enzymology and the Fountain of Youth: Repurposing Biology for Longevity
   Lim YP, Go MK, Raida M, Inoue T, Wenk MR, Keasling JD, Chang MW, Yew WS
   ACS Omega 3(9):11050-11061 (2018))
3. Genetically Engineered Bacteria as Vehicles for Localized Delivery of Therapeutics: An Application for Crohn’s Disease
   McKay R, Ghodasra M, Schardt K, Quan D, Pottash A, Shang W, Jay S, Payne G, Chang M, March J, Bentley W
   Bioengineering & Translational Medicine 3(3) (2018)
4. Synthetic biology toolkits and applications in Saccharomyces cerevisiae
   Chen B, Lee HL, Heng YC, Chua N, Teo WS, Choi WJ, Leong SS, Foo JL, Chang MW
   Biotechnology Advances 36(7):1870-1881 (2018)
5. Immunomodulation as Therapy for Fungal Infection: Are We Closer?
   Sam QH, Yew WS, Seneviratne CJ, Chang MW, Chai LYA
   Frontiers in Microbiology 9(1612) (2018)
6. Targeted approaches for in situ gut microbiome manipulation
   Lee HL, Shen H, Hwang IY, Ling H, Yew WS, Lee YS, Chang MW
   Genes 9:351 (2018)
7. Synthetic yeast genome reveals its versatility
   Foo JL, Chang MW
   Nature 557:647-648 (2018)
8. Engineering microbes for targeted strikes against human pathogens
   Hwang IY, Lee HL, Huang JG, Lim YY, Yew WS, Lee YS, Chang MW
   Cellular and Molecular Life Sciences 75:2719-2733 (2018)
9. Anhydrous polymer‐based coating with sustainable controlled release functionality for facile, efficacious impregnation, and delivery of antimicrobial peptides
   Lim K, Saravanan R, Chong KKL, Goh SHM, Chua RRY, Tambyah PA, Chang MW, Kline KA, Leong SSJ
   Biotechnology and Bioengineering 115:2000-2012 (2018)
10. Reprogramming probiotic Lactobacillus reuteri as a biosensor for Staphylococcus aureus derived AIP-I detection
    Lubkowicz D, Ho CL, Hwang IY, Yew WS, Lee YS, Chang MW
    ACS Synthetic Biology 7(5):1229-1237 (2018)
11. Rewriting the Metabolic Blueprint: Advances in Pathway Diversification in Microorganisms
    Hossain GS, Nadarajan SP, Zhang L, Ng TK, Foo JL, Ling H, Choi WJ, Chang MW
    Frontiers in Microbiology 9:155 (2018)
12. Engineered commensal microbes for diet-mediated colorectal-cancer chemoprevention
    Ho CL, Tan HQ, Chua KJ, Kang A, Lim KH, Ling KL, Yew WS, Lee YS, Thiery JP, Chang MW
    Nature Biomedical Engineering 2:27–37 (2018)

2017

1. Microscale Bioreactors for in situ characterization of GI epithelial cell physiology
   Costello C, Philipson M, Hartmanis L, Kwasnica M, Chen V, Hackam D, Chang MW, Bentley W, March J
   Scientific Reports 7:12515 (2017)
2. Autoinducer sensing microarrays by reporter bacteria encapsulated in hybrid supramolecular-polysaccharide hydrogels
   Li P, Dou XO, Müller M, Feng C, Chang MW, Frettlöh M, Schönherr H
   Macromolecular Bioscience. 1700176:8-16 (2017)
3. Encapsulation of Autoinducer Sensing Reporter Bacteria in Reinforced Alginate-based Microbeads
   Li P, Müller M, Chang MW, Frettlöh M, Schönherr H
   ACS Appl Mater Interfaces. 9(27):22321–22331 (2017)
4. Engineering a riboswitch-based genetic platform for the self-directed evolution of acid-tolerant phenotypes
   Pham HL, Wong A, Chua N, Teo WS, Yew WS, and Chang MW
   Nature Communications. 8:411 (2017)
5. Isolated Reporter Bacteria in Supramolecular Hydrogel Microwell Arrays
   Li P, Dou XQ, Feng C, Müller M, Chang MW, Frettlöh M, Schönherr H
   Langmuir. 33 (31):7799–7809 (2017)
6. Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models
   Hwang IY, Koh E, Wong A, March JC, Bentley WE, Lee YS, and Chang MW
   Nature Communications. 8:15028 (2017)
7. Designer probiotics for the prevention and treatment of human diseases
   Chua KJ, Kwok WC, Aggarwal N, Sun T, and Chang MW
   Current Opinion in Chemical Biology. 40:8-16 (2017)
8. Applying the design-build-test paradigm in microbiome engineering
   Pham HL, Ho CL, Wong A, Lee YS, and Chang MW
   Current Opinion in Biotechnology. 48:85–93 (2017)
9. The Fungal Mycobiome and Its Interaction with Gut Bacteria in the Host
   Sam QH, Chang MW, and Chai LYA
   International Journal of Molecular Sciences. 18, 330 (2017)
10. Microbiome engineering: Current applications and its future
    Foo JL, Ling H, Lee YS, and Chang MW
    Biotechnology Journal. 2, 1600099 (2017)

2016

1. Synthetic Biology in Asia: New Kids on the Block
   Chang MW
   ACS Synthetic Biology. 10.1021/acssynbio.6b00327 (2016)
2. Genetic Engineering of an Unconventional Yeast for Renewable Biofuel and Biochemical Production
   Yu A, Pratomo NK, Ng TK, Ling H, Cho HS, Leong S, Chang MW
   Journal of Visualized Experiments. doi:10.3791/54371 (2016)
3. Reprogrammable microbial cell-based therapeutics againstantibiotic-resistant bacteria
   Hwang IY, Koh E, Kima HR, Yew WS, Chang MW
   Drug Resistance Updates. 27 59–71 (2016)
4. A Two-Layer Gene Circuit for Decoupling Cell Growth from Metabolite Production
   Lo T, Chng SH, Teo WS, Cho HS, Chang MW
   Cell Systems. 3:133-143. (2016)
5. Metabolic engineering of Saccharomyces cerevisiae for the overproduction of short branched-chain fatty acids
   Yu A, Pratomo NK, Foo JL, Leong SSJ, Chang MW
   Metabolic Engineering. 34:36-43. (2016)
6. Whole-cell biocatalytic and de novo production of alkanes from free fatty acids in Saccharomyces cerevisiae
   Foo JL, Susanto AV, Keasling JD, Leong SSJ, Chang MW
   Biotechnology and Bioengineering. 114:232-237. (2016)

2015

1. Engineering transcription factors to improve tolerance against alkane biofuels in Saccharomyces cerevisiae
   Ling H, Pratomo NK, Teo WS, Liu R, Leong SSJ, Chang MW
   Biotechnology for Biofuels. 8:231. (2015)
2. Combinatorial metabolic engineering of Saccharomyces cerevisiae for terminal alkene production
   Chen BB, Lee DY, Chang MW
   Metabolic Engineering. 31:53-61. (2015)
3. Engineering Saccharomyces cerevisiae to produce odd chain-length fatty alcohols
   Jin Z, Wong CK, Foo JL, Ng J, Cao YX, Chang MW, Yuan YJ
   Biotechnology and Bioengineering. 113:842-51. (2015)
4. Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid short- and branched-chain alkyl esters biodiesel
   Teo W, Ling H, Yu AQ, Chang MW
   Biotechnology for Biofuels. 8:177. (2015)
5. Matrix-immobilized yeast for large-scale production of recombinant human lactoferrin
   Ho CL, Hwang IY, Loh K and Chang MW
   MedChemComm. 6:486 – 491. (2015)
6. Bacterial XylRs and synthetic promoters function as genetically encoded xylose biosensors in Saccharomyces cerevisiae
   Teo W and Chang MW
   Biotechnology Journal. 10:315-322. (2015)

2014

1. Production of fatty acid-derived valuable chemicals in synthetic microbes
   Yu AQ, Pratomo Juwono NK, Leong SSJ and Chang MW
   Frontiers in Bioengineering and Biotechnology. 2:78 (2014)
2. Microbial tolerance engineering toward biochemical production: from lignocellulose to products
   Ling H, Teo W, Chen B, Leong SSJ, Chang MW
   Current Opinion in Biotechnology. 29:99-106. (2014)
3. Site specific immobilization of a potent antimicrobial peptide onto silicone catheters: evaluation against urinary tract infection pathogens
   Mishra B, Basu A, Chua RRY, Saravanan R, Tambyah PA, Ho B, Chang MW, Leong SSJ
   Journal of Materials Chemistry. 2:1706-1716. (2014)
4. Reprogramming microbes to be a pathogen-seeking killer
   Hwang IY, Tan MH, Koh E, Ho CL, Poh CL, and Chang MW
   ACS Synthetic Biology. 3:228-237. (2014)
   Featured in The Economist, Nature News, Medical News, Science World Report, Science Daily, Vaccine News Daily, Food Quality News, MedCity News; Press release by American Chemical Society
5. Development and characterization of AND-gate dynamic controllers with a modular synthetic core promoter in Saccharomyces cerevisiae
   Teo W, Chang MW
   Biotechnology and Bioengineering. 111:144-151. (2014)
6. Therapeutic microbes for infectious disease
   Wong CK, Tan MH, Rasouliha B, Hwang IY, Ling H, Poh CL and Chang MW
   Methods in Molecular Biology. 1151:117-133. (2014)

2013

1. A predicted immunity protein confers resistance to pyocin S5 on a sensitive strain of Pseudomonas aeruginosa
   Rasouliha B, Ling H, Ho CL, Chang MW
   ChemBioChem. 14:2444-2446.47. (2013)
2. Transcriptome response to alkane biofuels in Saccharomyces cerevisiae: identification of efflux pumps involved in alkane tolerance
   Ling H, Chen BB, Kang A, Lee J, Chang MW
   Biotechnology for Biofuels. 6:95. (2013)
   Featured in Biofuels International
3. Bacterial FadR and synthetic promoters function as modular fatty acid sensor- regulators in Saccharomyces cerevisiae
   Teo W, Hee KS, Chang MW
   Engineering in Life Sciences. 13:456-463. (2013)
4. Designing a synthetic genetic circuit that enables cell density-dependent auto-regulatory lysis for macromolecule release
   Lo T, Tan MH, Hwang IY, Chang MW
   Chemical Engineering Science. 103:29-35. (2013)
5. Microbial engineering strategies to improve cell viability for biochemical production
   Lo T, Teo WS, Ling H, Chen BB, Kang A, Chang MW
   Biotechnology Advances. 31:903-914. (2013)
6. Transporter engineering for improved tolerance against alkane biofuels in Saccharomyces cerevisiae
   Chen BB, Ling H, Chang MW
   Biotechnology for Biofuels. 6:21. (2013)
   Featured in the Global Knowledge Center on Crop Biotechnology
7. Characterization of a quorum sensing device for synthetic biology design: experimental and modeling validation
   Saeidi N, Chang MW, and Poh CL
   Chemical Engineering Science. 103:91-99. (2013)
8. Systems-level characterization and engineering of oxidative stress tolerance in Escherichia coli under anaerobic condition
   Kang A, Tan MH, Ling H, Chang MW
   Molecular BioSystems. 9:285-295. (2013)

2012

1. Hildebrand solubility parameters of ionic liquids: effects of ionic liquid type, temperature and DMA fraction in ionic liquid
   Weerachanchai P, Chen Z, Leong SSJ, Chang MW, Lee JM
   Chemical Engineering Journal. 213:356-362. (2012)
2. Cefalexin-immobilized multi-walled carbon nanotubes show strong antimicrobial and anti-adhesion properties
   Qi X, Poernomo G, Xu R, Chang MW
   Chemical Engineering Science. 84:552-556. (2012)
3. Systems-level analysis of Escherichia coli response to silver nanoparticles: The roles of anaerobic respiration in microbial resistance
   Du H, Lo T, Sitompul J, and Chang MW
   Biochemical and Biophysical Research Communications. 424:657-662. (2012)
4. Improvement of biomass properties by pretreatment with ionic liquids for bioconversion process
   Weerachanchai P, Leong SSJ, Chang MW, Ching CB, Lee JM
   Bioresource Technology. 111:453-459. (2012)
5. Identification and reconstitution of genetic regulatory networks for improved microbial tolerance to isooctane
   Kang A, Chang MW
   Molecular BioSystems. 8:1350-1358. (2012)
6. The imminent role of protein engineering in synthetic biology
   Foo JL, Ching CB, Chang MW, Leong SSJ
   Biotechnology Advances. 30:541-549. (2012)

2011

1. Hollow fiber membrane decorated with Ag/MWNTs: Towards effective water disinfection and biofouling control
   Gunawan P, Guan C, Song X; Zhang Q, Leong S, Tang C, Chen Y, Chan-Park M, Chang MW, Wang K, Xu R
   ACS Nano. 5:10033-10040. (2011)
2. The roles of lipid in anti-biofilm efficacy of lipid–polymer hybrid nanoparticles encapsulating antibiotics
   Cheow WS, Chang MW, Hadinoto K
   Colloids and Surfaces A: Physicochemical and Engineering Aspects. 389: 158-165. (2011)
3. Engineering microbes to sense and eradicate Pseudomonas aeruginosa, a human pathogen
   Saeidi N, Wong CK, Lo T, Nguyen HX, Ling H, Leong SSJ, Poh CL, and Chang MW
   Molecular Systems Biology. 7:521. (2011)
   Highlighted in Nature Reviews Genetics 9:699, and Nature Reviews Microbiology 12:668.
   This paper was reported by over 70 news media agencies worldwide, such as Reuters, CBS News, Fox News, Chicago Tribune, Australia Broadcasting Corporation News, Nature, Science, Yahoo News, The Scientist, Discover Magazine, International Business Times, and National Geographic. Locally, this work has been selected as one of the top 10 discoveries in 2011 by Straits Times, and featured by most local news agencies including Channel News Asia.
4. Covalent immobilization of nisin on multi-walled carbon nanotubes: superior antimicrobial and anti-biofilm properties
   Qi X, Poernomo G, Wang K, Chen Y, Chan-Park MB, Xu R, Chang MW
   Nanoscale. 3:1874-1880. (2011)
5. Targeting FK506 binding proteins to fight malarial and bacterial infections: Current advances and future perspectives
   Bharatham N, Chang MW, Yoon HS
   Current Medicinal Chemistry. 18:1874-1889. (2011)
6. A photopolymerized antimicrobial hydrogel coating derived from epsilon-poly-l-lysine
   Zhou C, Peng L, Qi X, Lamrani M, Chang MW, Leong SS, Chan-Park MB
   Biomaterials. 32:2704-2712. (2011)
7. A polycationic antimicrobial and biocompatible hydrogel with microbe membrane suctioning ability
   Li P, Poon YF, Li W, Zhu HY, Yeap SH, Cao Y, Qi X, Zhou C, Lamrani M, Beuerman RW, Kang ET, Mu Y, Li CM, Chang MW, Leong SS, and Chan-Park MB
   Nature Materials. 10:149-156. (2011)

2010

1. Vaccinia-related kinase 1 is required for the maintenance of undifferentiated spermatogonia in mouse male germ cells
   Choi YH, Park CH, Kim W, Ling H, Kang A, Chang MW, Im SK, Jeong HW, Kong YY, Kim KT
   PLoS One. 5:e15254. (2010)
2. The absence of the luxS gene increases swimming motility and flagella synthesis in Escherichia coli K12
   Ling H, Kang A, Tan MH, Qiao B, and Chang MW
   Biochemical and Biophysical Research Communications. 401:521-526. (2010)
3. A simple and effective plating method to screen polycyclic aromatic hydrocarbon-degrading bacteria under various redox conditions
   Um Y, Chang MW, and Holoman TP
   Applied Microbiology and Biotechnology. 88:291-297. (2010)
4. iTRAQ-coupled 2-D LC-MS/MS analysis of protein profile in Escherichia coli incubated with human Neutrophil Peptide 1 – Potential in Antimicrobial Strategy
   Zhou Y, Lamrani M, Chan-Park MB, Leong S, Chang MW, and Chen WN
   Rapid Communications in Mass Spectrometry. 24:2787-2790. (2010)
5. Novel short antibacterial and antifungal peptides with low cytotoxicity: efficacy and action mechanisms
   Qi X, Zhou C, Li P, Xu W, Cao Y, Ling H, Chen WN, Li CM, Xu R, Lamrani M, Mu Y, Leong S, Chang MW, and Chan-Park MB
   Biochemical and Biophysical Research Communications. 398:594-600. (2010)
6. Antibacterial efficacy of inhalable Levofloxacin-loaded polymeric nanoparticles against E. coli biofilm cells: The effect of antibiotic release profile
   Cheow WS, Chang MW, Hadinoto K
   Pharmaceutical Research. 27:1597-1609. (2010)
7. A predicted S-type pyocin shows a bactericidal activity against clinical Pseudomonas aeruginosa isolates through membrane damage
   Ling H, Saedi N, Rasouliha BH, and Chang MW
   FEBS Letters. 584:3354-3358. (2010)
8. High potency and broad-spectrum antimicrobial peptides synthesized via ring-opening polymerization of alpha-aminoacid-N-carboxyanhydrides
   Zhou C, Qi X, Li P, Chen WN, Lamrani M, Chang MW, Leong S and Chan-Park MB
   Biomacromolecules. 11:60-67. (2010)
9. Antibacterial efficacy of inhalable antibiotic-encapsulated biodegradable polymeric nanoparticles against E. coli biofilm cells
   Cheow WS, Chang MW, and Hadinoto K.
   Journal of Biomedical Nanotechnology. 6:1-13. (2010)

2009

1. Sharper and faster “Nano Darts” kill more bacteria: a study of antibacterial activity of individually dispersed pristine single-walled carbon nanotube
   Liu S, Wei L, Hao L, Fang N, Chang MW, Xu R, Yang Y, and Chen Y
   ACS Nano. 3:3891-3902. (2009)
2. A time-course transcriptome analysis of Escherichia coli with direct electrochemistry behavior in microbial fuel cells
   Qiao Y, Li CM, Lu Z, Ling H, Kang A and Chang MW
   Chemical Communications 41:6183-6185 (2009)
3. Strain improvement and process development for biobutanol production
   Kharkwal S, Karimi IA, Chang MW, and Lee DY
   Recent Patents on Biotechnology 3:202-210. (2009)

2008

1. Deposition of Silver Nanoparticles on Multiwalled Carbon Nanotubes Grafted with Hyperbranched Poly(amidoamine) and Their Antimicrobial Effects
   Yuan W, Jiang G, Jianfei C, Xiaobao Q, Xu R, Chang MW, Chen Y, Lim SY, Dai J, and Chan-Park MB
   Journal of Physical Chemistry C 112:18754-18759. (2008)
2. Molecular characterization of surfactant-driven microbial community changes in anaerobic phenanthrene-degrading cultures under methanogenic conditions
   Chang MW, Holoman TP, and Yi H
   Biotechnology Letters 30:1595-1601. (2008)
3. Microarray analysis of toxicogenomic effects of triclosan on Staphylococcus aureus
   Jang H, Chang MW, Toghrol F, and Bentley WE
   Applied Microbiology and Biotechnology 78:695-707. (2008)

2007

1. Toxicogenomic response to chlorination includes induction of major virulence genes in Staphylococcus aureus
   Chang MW, Toghrol F, and Bentley WE
   Environmental Science and Technology 41:7570-7575. (2007)
2. Comparative global transcription analysis of sodium hypochlorite, peracetic acid, and hydrogen peroxide in Pseudomonas aeruginosa
   Small D, Chang MW, Toghrol F, and Bentley WE
   Applied Microbiology and Biotechnology 76:1093-1105. (2007)
3. Toxicogenomic analysis of sodium hypochlorite antimicrobial mechanisms in Pseudomonas aeruginosa
   Small D, Chang MW, Toghrol F, and Bentley WE
   Applied Microbiology and Biotechnology 74:176-185. (2007)

2006

1. Toxicogenomic response of Staphylococcus aureus to peracetic acid
   Chang MW, Toghrol F, and Bentley WE
   Environmental Science and Technology 40:5124-5131. (2006)
2. Polycyclic aromatic hydrocarbon (PAH) degradation coupled to methanogenesis
   Chang MW, Um Y, and Holoman TP
   Biotechnology Letters 28:425-430. (2006)
3. Global transcriptome analysis of Staphylococcus aureus response to hydrogen peroxide
   Chang MW, Small D, Toghrol F, and Bentley WE
   Journal of Bacteriology 184:1648-1659. (2006).

2005

1. Microarray analysis of Pseudomonas aeruginosa reveals induction of pyocin genes in response to hydrogen peroxide
   Chang MW, Small D, Toghrol F, and Bentley WE
   BMC Genomics 6:115. (2005)
2. Microarray analysis of toxicogenomic effects of peracetic acid on Pseudomonas aeruginosa
   Chang MW, Small D, Toghrol F, and Bentley WE
   Environmental Science and Technology 39:5893-5899. (2005)
3. Molecular characterization of anaerobic microbial communities from benzene-degrading sediments under methanogenic conditions
   Chang MW, Um Y, and Holoman TP
   Biotechnology Progress 21:1789-1794. (2005)
4. Molecular characterization of polycyclic aromatic hydrocarbon (PAH)-degrading methanogenic communities
   Chang MW, Um Y, Hoffman B, and Holoman TP
   Biotechnology Progress 21:682-688. (2005)

2001

1. Anaerobic polycyclic aromatic hydrocarbon (PAH)-degrading enrichment cultures under methanogenic conditions
   Chang MW, Jones T, and Holoman TP
   Bioremediation of Recalcitrant Organic Compounds, Battelle Press, Columbus, Ohio. p. 205-210. (2001)